May 26 2009

At the Bridge Table, Clues to a Lucid Old Age

Klint Finley

So far, scientists here have found little evidence that diet or exercise affects the risk of dementia in people over 90. But some researchers argue that mental engagement — doing crossword puzzles, reading books — may delay the arrival of symptoms. And social connections, including interaction with friends, may be very important, some suspect. In isolation, a healthy human mind can go blank and quickly become disoriented, psychologists have found.

“There is quite a bit of evidence now suggesting that the more people you have contact with, in your own home or outside, the better you do” mentally and physically, Dr. Kawas said. “Interacting with people regularly, even strangers, uses easily as much brain power as doing puzzles, and it wouldn’t surprise me if this is what it’s all about.”

New York Times: At the Bridge Table, Clues to a Lucid Old Age

An article about Red Bull drinking 92 year old bridge players is a good compliment to this New Yorker article about 20 and 30 somethings trying to squeeze as much performance out of their brains as possible.

See also:

Blue Zones

5 real products of the 90s cyberpunk & transhumanist hype

Could Caffeine Reduce Risk of Alzheimer’s Disease?

Also, whenever I start to worry about growing older, I take comfort in what Alejandro Jodorowsky had to say in this interview:

You’re 77 now. How are you coping with growing older?

It’s fantastic! I like it a lot. I don’t want to change myself. If you said, Do you want to be 40 years old [again] and I would say, maybe my body, but not my mind. It’s a nightmare, a social nightmare to get old – to get Parkinson’s, to become an idiot, but every day the brain is making new connections and is developing, like the universe. Your soul is getting better and better because you are losing what is not necessary. It’s fantastic to get old! It’s an incredible feeling of freedom, incredible!

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May 4 2009

Mechanisms Of Self-control Pinpointed In Brain

Klint Finley

When you’re on a diet, deciding to skip your favorite calorie-laden foods and eat something healthier takes a whole lot of self-control–an ability that seems to come easier to some of us than others. Now, scientists from the California Institute of Technology (Caltech) have uncovered differences in the brains of people who are able to exercise self-control versus those who find it almost impossible.

The key? While everyone uses the same single area of the brain to make these sorts of value-laden decisions, a second brain region modulates the activity of the first region in people with good self-control, allowing them to weigh more abstract factors–healthiness, for example–in addition to basic desires such as taste to make a better overall choice.

These findings not only provide insight into the interplay between self-control and decisionmaking in dieters, but may explain how we make any number of decisions that require some degree of willpower. [...]

The next step, the researchers say, is to come up with ways to engage the DLPFC in the decisions made by people with poor self-control under normal conditions. For instance, Hare says, it might be possible to kick the DLPFC into gear by making the health qualities of foods more salient for people, rather than asking them to make the effort to judge a food’s health benefits on their own. “If we highlight the fact that ice cream is unhealthy just before we offer it,” he notes, “maybe we can reduce its value in advance, give the person a head start to making a better decision.”

Science Daily: Mechanisms Of Self-control Pinpointed In Brain

(via OVO)

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Apr 22 2009

Researchers use brain interface to post to Twitter

Klint Finley

Just 23 characters long, his message, “using EEG to send tweet,” demonstrates a natural, manageable way in which “locked-in” patients can couple brain-computer interface technologies with modern communication tools.

A University of Wisconsin-Madison biomedical engineering doctoral student, Wilson is among a growing group of researchers worldwide who aim to perfect a communication system for users whose bodies do not work, but whose brains function normally. Among those are people who have amyotrophic lateral sclerosis (ALS), brain-stem stroke or high spinal cord injury.

Some brain-computer interface systems employ an electrode-studded cap wired to a computer. The electrodes detect electrical signals in the brain - essentially, thoughts - and translate them into physical actions, such as a cursor motion on a computer screen. “We started thinking that moving a cursor on a screen is a good scientific exercise,” says Justin Williams, a UW-Madison assistant professor of biomedical engineering and Wilson’s adviser. “But when we talk to people who have locked-in syndrome or a spinal-cord injury, their No. 1 concern is communication.”

In collaboration with research scientist Gerwin Schalk and colleagues at the Wadsworth Center in Albany, N.Y., Williams and Wilson began developing a simple, elegant communication interface based on brain activity related to changes in an object on screen.

The interface consists, essentially, of a keyboard displayed on a computer screen. “The way this works is that all the letters come up, and each one of them flashes individually,” says Williams. “And what your brain does is, if you’re looking at the ‘R’ on the screen and all the other letters are flashing, nothing happens. But when the ‘R’ flashes, your brain says, ‘Hey, wait a minute. Something’s different about what I was just paying attention to.’ And you see a momentary change in brain activity.”

Wilson, who used the interface to post the Twitter update, likens it to texting on a cell phone. “You have to press a button four times to get the character you want,” he says of texting. “So this is kind of a slow process at first.”

WisBusiness: Researchers use brain interface to post to Twitter

(via Richard Metzger)

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Apr 6 2009

Forget erasing bad memories, new research may help unlearn traumatic events

Klint Finley

The discovery that mGLuR5 is integral to both extinguishing fearful memories and acquiring new ones could open the door to developing pharmaceuticals to treat PTSD. “You could hypothetically develop a drug that will isolate the receptor,” says Xu. “It could make it easier for a patient to form new memories and override traumatic events.” Currently, PTSD is treated with a combination of exposure therapy, in which patients relive traumatic events in safe environments, and SSRIs or tricyclic antidepressants. Now that they’ve identified this pathway, the team Xu is a part of will focus on eliminating mGluR5 in specific regions of the brain, he says, probably starting with the amygdala. As for the promise of erasing bad memories, Xu thinks it’s not a good idea. “It’s more appropriate to remember [a traumatic] event,” he says. “You just don’t want it to affect your daily life.”

SEED: Getting Over It

(Via - Can’t remember where I found this. Let me know if you think I stole this from you)

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Feb 20 2009

Five Brain-Manipulating Technologies That Prove Dollhouse Exists Right Now

Klint Finley

brain manipulation

1. We can erase people’s memories.
2. We can regulate people’s moods with microchips.
3. We can use brain implants to steer animals left and right.
4. Infrared brain scans can predict what people want.
5. Human-computer interfaces link human brains directly to computers.

Full Story: io9

(via OVO)

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Feb 14 2009

Oliver Sacks Discusses Hallucination

Bill Whitcomb

Oliver Sacks Sees Things Differently Now

As part of their “TED Q & A” series, Wired published an interview with Neurologist Oliver Sacks where he discusses visual hallucination and his experiences after losing central vision in his right eye.

To compensate for the missing visual data once supplied by his right eye, his brain has projected hallucinations and patterns onto the dark stage -– a phenomenon common to people who have lost their sight. Ever curious about the mind’s varied responses to disease, Sacks has chronicled it all in a series of unpublished journals containing drawings and writings.

Last year at the Technology Entertainment and Design conference, one of the most popular talks was given by Jill Bolte Taylor, a neuroanatomist who described what occurred in her mind and body as she experienced a stroke. On Thursday, Sacks will speak at TED about the mysteries of perception and what occurs in the mind when the body loses its senses. He spoke with Wired.com about how the mind sometimes plays tricks on what we see and what it has meant to lose part of his vision.

The complete article can be found here.

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Feb 11 2009

New Device Reads Minds Pretty Well

Klint Finley

Hmmmm…

Canadian researchers say they can glean simple preferences from a person’s brain by shining near-infrared light into the noggin.

The study, reported in the Journal of Neural Engineering, demonstrated the ability to decode a person’s preference for one of two drinks with 80 percent accuracy by measuring the intensity of near-infrared light absorbed in brain tissue, the scientists said in a statement today.

“This is the first system that decodes preference naturally from spontaneous thoughts,” says Sheena Luu, a University of Toronto doctoral student in biomedical engineering who led the work under the supervision of Tom Chau, a specialist in pediatric rehab engineering at the university’s Bloorview Kids Rehab center.

Full Story: Live Science

(via Wade)

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Feb 6 2009

Red and Blue Brain States

Bill Whitcomb

 

It’s long been known that color has powerful effects.  Red light measurably raises metabolism and increases grip strength.  Blue calms and cools.  In advertising, blue corporate logos are generally used to convey stability and trustworthiness, while red is used to convey energy and power.

A new study from the University of British Columbia now finds that blue promotes creativity and red aids attention to detail.

To test alternative explanations for the findings, Zhu’s team showed that neither red nor blue influenced mood. Test subjects also spent the same amount of time on their tasks, suggesting that neither color affected their motivation.

The colors appeared to enhance performance, but not to impair it. Red- and white-primed students had similar creativity scores, while blue- and white-primed students were equal on attention tasks.

Asked about the implications, Zhu suggested that people engaged in creative tasks surround themselves with blue, and with red when trying to focus.

An article in Wired by Brandon Keim can be found here.  The results are published in the current issue of Science:  “Blue or Red? Exploring the Effect of Color on Cognitive Task Performances.” By Ravi Mehta and Juliet Zhu. Science, Vol. 324, Issue 5915, Feb. 5, 2009.

 

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Jan 31 2009

Reading Changes Brain as Well as Mind

Bill Whitcomb

Brains scans show activation during narrative.

An article by Gerry Everding from Physorg.com discusses reseach demonstrating that various regions of the brain are activated by reading fiction.

A new brain-imaging study is shedding light on what it means to “get lost” in a good book — suggesting that readers create vivid mental simulations of the sounds, sights, tastes and movements described in a textual narrative while simultaneously activating brain regions used to process similar experiences in real life.

“Psychologists and neuroscientists are increasingly coming to the conclusion that when we read a story and really understand it, we create a mental simulation of the events described by the story,” says Jeffrey M. Zacks, study co-author and director of the Dynamic Cognition Laboratory at Washington University in St. Louis.

The study, forthcoming in the journal Psychological Science, is one of a series in which Zacks and colleagues use functional magnetic resonance imaging (fMRI) to track real-time brain activity as study participants read and process individual words and short stories.

Hey, pathworking and other forms of guided imagery actually do something measurable!  Why, that means that role-playing games…umh…uh, oh.

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Jan 20 2009

Self Awareness: The Last Frontier

TiamatsVision

“One of the last remaining problems in science is the riddle of consciousness. The human brain—a mere lump of jelly inside your cranial vault—can contemplate the vastness of interstellar space and grapple with concepts such as zero and infinity. Even more remarkably it can ask disquieting questions about the meaning of its own existence. “Who am I” is arguably the most fundamental of all questions.

It really breaks down into two problems—the problem of qualia and the problem of the self. My colleagues, the late Francis Crick and Christof Koch have done a valuable service in pointing out that consciousness might be an empirical rather than philosophical problem, and have offered some ingenious suggestions. But I would disagree with their position that the qualia problem is simpler and should be addressed first before we tackle the “Self.” I think the very opposite is true. I have every confidence that the problem of self will be solved within the lifetimes of most readers of this essay. But not qualia.”

(via Edge. h/t: Integral Praxis)

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Jan 9 2009

How The City Hurts Your Brain

TiamatsVision

“The city has always been an engine of intellectual life, from the 18th-century coffeehouses of London, where citizens gathered to discuss chemistry and radical politics, to the Left Bank bars of modern Paris, where Pablo Picasso held forth on modern art. Without the metropolis, we might not have had the great art of Shakespeare or James Joyce; even Einstein was inspired by commuter trains.

And yet, city life isn’t easy. The same London cafes that stimulated Ben Franklin also helped spread cholera; Picasso eventually bought an estate in quiet Provence. While the modern city might be a haven for playwrights, poets, and physicists, it’s also a deeply unnatural and overwhelming place.

Now scientists have begun to examine how the city affects the brain, and the results are chastening. Just being in an urban environment, they have found, impairs our basic mental processes. After spending a few minutes on a crowded city street, the brain is less able to hold things in memory, and suffers from reduced self-control. While it’s long been recognized that city life is exhausting — that’s why Picasso left Paris — this new research suggests that cities actually dull our thinking, sometimes dramatically so. “The mind is a limited machine,”says Marc Berman, a psychologist at the University of Michigan and lead author of a new study that measured the cognitive deficits caused by a short urban walk. “And we’re beginning to understand the different ways that a city can exceed those limitations.”

(via Boston.com)

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Jan 6 2009

Mattel Mindflex - brainwave “levitation” toy?

Klint Finley

mattel mindflex

Mattel’s keeping mum about the technology behind its Mindflex game, but – according to several online sources – the game requires the user to wear a headset equipped with sensors that measure brainwave activity.

This ‘activity’ is then used to guide a small foam ball through an obstacle course of hoops, which can be customised by the gamer.

It’s still unclear how the ball is kept in the air throughout its journey around the obstacle course. Some reports have claimed that a fan’s used, whilst other sources have said that Epoc-esque technology is the key to Mindflex’s power.

Full Story: Register Hardware

(via Grinding)

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Dec 21 2008

Brain Injuries Linked to Spirituality

TiamatsVision

“Two University of Missouri psychologists are proposing “a neurophysiological model of spiritual experience” that explains what is happening inside the brain when people experience feelings of selflessness and transcendence. The model “suggests that all individuals, regardless of cultural background or religion, experience the same neurophysiological/neuropsychological functions during spiritual experiences,” according to co-authors Brick Johnstone and Bret A. Glass. It also attempts to explain why these brain activities are interpreted in such different ways by people from different religious traditions and cultures.

Their work, which is detailed in a newly published paper in the journal Zygon, builds on that of researchers such as Dr. Andrew Newberg, who conducted MRI scans of meditating Buddhist monks and Catholic nuns engaging in contemplative prayer. As Miller-McCune reported in October, such activity is associated with increased activity in the frontal lobe, combined with decreased activity in another part of the brain, the parietal lobe.

The Missouri researchers approached the issue from another angle altogether, studying the spiritual experiences of people who suffered traumatic brain injuries. They asked 26 adults who had suffered such injuries about their personal spiritual experiences, the amount of time they devote to spiritual or religious practices and the degree to which they feel close to God or some other spiritual entity.”

(via Miller-McCune. h/t: Precious Metal)

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Dec 13 2008

Scientists create device that can project images from dreams

Klint Finley

Can this possibly be true?

A team of Japanese scientists have created a device that enables the processing and imaging of thoughts and dreams as experienced in the brain to appear on a computer screen.

While researchers have so far only created technology that can reproduce simple images from the brain, the discovery paves the way for the ability to unlock people’s dreams and other brain processes.

A spokesman at ATR Computational Neuroscience Laboratories said: “It was the first time in the world that it was possible to visualise what people see directly from the brain activity.

Full Story: the Telegraph

Reminds me of the movie Until the End of the World

(thanks Bill)

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Nov 19 2008

Amazing Story of a Man Who Survived Being Buried 40 Days

TiamatsVision

fakir lying on thorns

“According to a fascinating report printed in the London Telegraph in 1880, a man was buried “in a condition of apparent death’ for 40 days and survived. No tricks or tomfoolery were involved, so how did he do it? It’s often the case that when someone professes to be able do something remarkable, that great gift of human nature kicks in - skepticism. So when Maharajah Ranjeet Sing heard from an Indian fakir who claimed he could come back to life after being buried for several months in an apparent state of death, the Maharajah could only reply with one statement - proof or it didn’t happen.

At once, the fakir, named Haridas, was summonsed before the Maharajah - who regarded the idea as possibly fraudulent - to act out exactly how he could accomplish this amazing feat. In full view of the Maharajah and nobles of the court, within a short time, the fakir appeared comatosed. One of the witnesses at the time, an Honorable Captain Osborn, made his own account of the event:

“When every spark of life had seemingly vanished, he was … wrapped up in the linen on which he had been sitting, and on which the seal of Ranjeet Sing was placed. The body was then deposited in a chest, on which Ranjeet Sing, with his own hand, fixed a heavy padlock. The chest was carried outside the town and buried in a garden belonging to the Minister; barley was sown over the spot, a wall created around it, and sentinels posted.” 

So was the mistrust of the Maharajah.”

(via Environmental Graffiti)

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Oct 23 2008

Who funds psychedelic drug research?

Klint Finley

Also known as Lady Neidpath, Feilding is not a scientist, but spends a six-figure sum of her own money each year to explore the inner workings of our mind: how we think; where creativity comes from; and how we can harness this knowledge. Through her charitable trust, the Beckley Foundation, she instigated the first scientific trial in 35 years to use LSD on human subjects. Based in Beckley Park, the Oxfordshire estate where Feilding has spent all her life, the foundation’s remit is to push for drug policy reform and fund research that will delve into the altered states of consciousness induced by meditation, deep breathing and powerful psychoactive drugs such as LSD. Even trepanning, the ancient practice of drilling a hole in the skull, is a line of modern inquiry as a treatment for Alzheimer’s. It is research that - in the UK at least - no one else appears willing to back.

“We are on the verge of making real breakthroughs,”  she says.

Why would an English Lady want to spend her money on high-risk projects with poor-to-zero financial returns? Feilding’s fascination with consciousness started at an early age. Interested in spirituality through her Roman Catholic upbringing, she was sent aged 16 to India to visit her godfather, a Buddhist monk. She went on to study mysticism and comparative religion at Oxford University and dabbled with drugs throughout the Sixties. But her interest in the medical applications of such substances sprung from a friendship with Albert Hofmann, the Swiss scientist who invented LSD, and who pushed for the medical benefits of the drug to be investigated. Hofmann died this year aged 102, shortly before the foundation published his last book, Hofmann’s Elixir: LSD and the New Eleusis, a collection of his essays and lectures.

Full Story: Times

(via OVO)

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Oct 23 2008

Scientists Erase Specific Memories in Mice

Klint Finley

It sounds like science fiction, by scientists say it might one day be possible to erase undesirable memories from the brain, selectively and safely.

Using a complex genetic approach, U.S. and Chinese researchers believe they have done just that in mice, but the feat is far from being tested on humans.

Study co-author Joe Z. Tsien, co-director of the Brain & Behavior Discovery Institute at the Medical College of Georgia, Augusta, says the “work reveals a molecular mechanism of how [memory deletion] can be done quickly and without doing damage to brain cells.”

Full Story: Yahoo!

(via Cryptogon)

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Oct 3 2008

Think You’re Multitasking? Think Again

TiamatsVision

“Don’t believe the multitasking hype, scientists say. New research shows that we humans aren’t as good as we think we are at doing several things at once. But it also highlights a human skill that gave us an evolutionary edge. As technology allows people to do more tasks at the same time, the myth that we can multitask has never been stronger. But researchers say it’s still a myth - and they have the data to prove it.

Humans, they say, don’t do lots of things simultaneously. Instead, we switch our attention from task to task extremely quickly. A case example, researchers say, is a group of people who focus not on a BlackBerry but on a blueberry - as in pancakes.

Diner Cook: A Task Master:

To make it as a short-order cook, you must be able to keep a half-dozen orders in your head while cracking eggs, flipping pancakes, working the counter, and refilling coffee cups. And at a restaurant like the Tastee Diner, in Bethesda, Md., the orders come in verbally, not on a ticket. Chocolate chip pancakes, scrambled with sausage, order of french fries, rye toast - they’re small tasks. On a busy day, though, they add up to a tough job for Shawn Swinson. “My first month here, I was ready to walk out the door,” he said. Asked what it feels like when he’s in the middle of rush hour, Swinson said, “Like you’re in an insane asylum. It’s almost unbearable.”

“It’s singularly the most difficult job in this type of operation,” Long said. “Four cooks. Five waitresses. Bus staff. Host. Getting them in and out.” Speed and accuracy are at a premium - especially when the customers are multitasking, too. Lunchtime is the worst, Long said. “People may have an errand to run. Maybe go to the bank and pick up dry cleaning, and eat. All within an hour, whatever time they have.” It’s all part of life these days. We answer e-mails while yapping on the phone. We schedule appointments while driving and listening to the radio. And it seems as if we’re focusing on all these tasks simultaneously, as if we’ve become true masters of doing 10 things at once. But, brain researchers say, that’s not really the case.”

(via NPR)

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Sep 19 2008

India becomes first country to use brain scanning in courts

Klint Finley

The new technology is, to its critics, Orwellian. Others view it as a silver bullet against terrorism that could render waterboarding and other harsh interrogation methods obsolete. Some scientists predict the end of lying as we know it.

Now, well before any consensus on the technology’s readiness, India has become the first country to convict someone of a crime relying on evidence from this controversial machine: a brain scanner that produces images of the human mind in action and is said to reveal signs that a suspect remembers details of the crime in question.

Full Story: New York Times

(via Disinfo)

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Sep 19 2008

Time Magazine: The Army’s Totally Serious Mind-Control Project

Klint Finley

army_brain_wave_0912 Time Magazine: The Armys Totally Serious Mind-Control Project

Soldiers barking orders at each other is so 20th Century. That’s why the U.S. Army has just awarded a $4 million contract to begin developing “thought helmets” that would harness silent brain waves for secure communication among troops. Ultimately, the Army hopes the project will “lead to direct mental control of military systems by thought alone.”

If this sounds insane, it would have been as recently as a few years ago. But improvements in computing power and a better understanding of how the brain works have scientists busy hunting for the distinctive neural fingerprints that flash through a brain when a person is talking to himself. The Army’s initial goal is to capture those brain waves with incredibly sophisticated software that then translates the waves into audible radio messages for other troops in the field. “It’d be radio without a microphone, ” says Dr. Elmar Schmeisser, the Army neuroscientist overseeing the program. “Because soldiers are already trained to talk in clean, clear and formulaic ways, it would be a very small step to have them think that way.”

Full Story: Time

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Sep 18 2008

Study Finds Possible Biological Basis for Political Positions

Klint Finley

People who startle easily in response to threatening images or loud sounds seem to have a biological predisposition to adopt conservative political positions on many hot-button social issues, according to unusual new research being published today.

The finding — certain to stir debate in the middle of a presidential campaign — suggests that people who are particularly sensitive to signals of visual and auditory threats also tend to adopt a more defensive stance on political issues, from immigration and gun control to defense spending and patriotism. People who are less sensitive to potential threats, by contrast, seem predisposed to adopt more liberal positions on those issues.

(Thanks Bill!)

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Sep 11 2008

World’s Largest-ever Study Of Near-Death Experiences

TiamatsVision

“The University of Southampton is launching the world’s largest-ever study of near-death experiences this week. The AWARE (AWAreness during REsuscitation) study is to be launched by the Human Consciousness Project of the University of Southampton - an international collaboration of scientists and physicians who have joined forces to study the human brain, consciousness and clinical death.

The study is led by Dr Sam Parnia, an expert in the field of consciousness during clinical death, together with Dr Peter Fenwick and Professors Stephen Holgate and Robert Peveler of the University of Southampton. Following a successful 18-month pilot phase at selected hospitals in the UK, the study is now being expanded to include other centres within the UK, mainland Europe and North America. “Contrary to popular perception,” Dr Parnia explains, “death is not a specific moment. It is a process that begins when the heart stops beating, the lungs stop working and the brain ceases functioning - a medical condition termed cardiac arrest, which from a biological viewpoint is synonymous with clinical death.”

(via Science Daily)

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Sep 4 2008

Zen Training Speeds The Mind’s Return After Distraction, Study Suggests

Klint Finley

Experienced Zen meditators can clear their minds of distractions more quickly than novices, according to a new brain imaging study.

After being interrupted by a word-recognition task, experienced meditators’ brains returned faster to their pre-interruption condition, researchers at Emory University School of Medicine found.
Giuseppe Pagnoni, PhD, Emory assistant professor of psychiatry and behavioral sciences, and co-workers used functional magnetic resonance imaging (fMRI) to examine changes in blood flow in the brain when people meditating were interrupted by stimuli designed to mimic the appearance of spontaneous thoughts.

The study compared 12 people from the Atlanta area with more than three years of daily practice in Zen meditation with 12 others who had never practiced meditation.

Full Story: Science Daily

(via OVO)

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Aug 25 2008

Potential military applications of cognitive technologies

Klint Finley

Drugs that make soldiers want to fight. Robots linked directly to their controllers’ brains. Lie-detecting scans administered to terrorist suspects as they cross U.S. borders.

These are just a few of the military uses imagined for cognitive science — and if it’s not yet certain whether the technologies will work, the military is certainly taking them very seriously.

“It’s way too early to know which — if any — of these technologies is going to be practical,” said Jonathan Moreno, a Center for American Progress bioethicist and author of Mind Wars: Brain Research and National Defense. “But it’s important for us to get ahead of the curve. Soldiers are always on the cutting edge of new technologies.”

Full Story: Wired

(via Cryptogon)

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Aug 19 2008

Decoding The Emotional Brain

TiamatsVision

“Being a neurologist in the era of fMRI scanners must feel like being a kid in a candy shop. What’s going in there while we’re, say, shopping? How about reading? Watching campaign ads? Now that we have a way to take real-time images of the brain at work, the scientific possibilities are endless.

On the surface, the experiment at the heart of this story might seem pretty narrow. It focuses on a rare disorder called pseudobulbar affect, which afflicts only people with ALS, or Lou Gehrig’s disease - a far cry from the universal rites of shopping or reading. But what’s fascinating about pseudobulbar is the light it might shed on all of us, and one of the most primal and mysterious human experiences of all: emotion.

People with pseudobulbar get happy and sad, just like the rest of us. They laugh and cry like the rest of us too. But then sometimes, something else happens: They keep going. And going. In this video, you can see how what looks like a laughing fit morphs into something else entirely. It’s as if the laughing and crying mechanisms have become detached from whatever part of the brain triggered the emotion in the first place. Maybe - and this is the hope of scientists Howard Rosen and Robert Levenson - by seeing that disconnect take place in real time through the fMRI, we’ll understand, for the first time, how emotion plays out in people without pseudobulbar affect.”

(via Quest)

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